The quantum curve conjecture claims that one can associate a differential equation to a spectral curve, whose solution can be reconstructed by topological recursion applied to the original spectral curve. I will explain how starting just from loop equations, one can construct a system of PDEs which will annihilate the wave function built from topological recursion, solving the conjecture affirmatively for all hyperelliptic curves. The families of spectral curves can be parametrized with the so-called times, which can be defined as periods on second type cycles on the curves. These deformation parameters giving rise to families of spectral curves will play a key role when producing our system of PDEs. Our system of PDEs can be used to prove that the WKB solution of many isomonodromic systems coincide with the topological recursion wave function. If time permits, I will comment on how to generalize this procedure to spectral curves of arbitrary rank, but with simple ramifications, which is work in progress.